A Escrava Isaura (Portuguese pronunciation: [a (i)ʃˈkɾavɐ iˈzawɾɐ], Isaura, The Slave Girl) is a novel written by the Brazilian writer Bernardo Guimarães. It was first published in 1875 by Casa Garnier publishers in Rio de Janeiro. With this novel, Bernardo Guimarães became very famous throughout that country, even said to be admired by Brazil's last Emperor Dom Pedro II.

In 1976, a Brazilian telenovela adaptation produced by Rede Globo was titled Escrava Isaura. It was a worldwide success.

In 2004, a second Brazilian telenovela was produced by TV Record. It was also titled A Escrava Isaura. This adaptation also aired on Telemundo in the United States. This version was dubbed into Spanish and titled La Esclava Isaura.

The title character is so pale-skinned that she is "almost white", making her the Brazilian equivalent of Eliza, from Harriet Beecher Stowe's Uncle Tom's Cabin.